Endocrine Abstracts

Objective: The project was designed to Assess And IMprove (AAIM) the practice of healthcare professionals (HCPs) around the corticosteroid sick-day rule, involved in caring for transplant and oncology patients requiring treatment with corticosteroids long-term.Introduction: Corticosteroids are widely prescribed drugs in oncology and post-transplant patients. Long-term treatment with corticosteroids dose, which equals pre...

Introduction: Laparoscopic unilateral adrenalectomy (UA) is a frequent approach in managing patients with structural and functional adrenal disorders. Suboptimal assessment post-operatively can result in multiple adverse consequences, including adrenal insufficiency. However, the optimal post-operative assessment and long-term effects on physical and mental health have not been sufficiently documented. This study aims to investigate the long-term effects of UA...

Adrenal tumors (ATs) are uncommon in children and adolescents. The aim of this nation-wide retrospective registry-based cohort study was to characterise the various ATs in this population and demonstrate their differences from ATs in adults. All patients under the age of 21 in Sweden with verified adrenal lesions according to ICD-codes between 2005 and 2019 were identified in linked nation-wide registries. Out of the total 232 patients, 121 (52.2%) were boys, with boy predomin...

Introduction: The assessment of the glycemic regulation of patients with Type 1 Diabetes Mellitus is necessary, in order to design an individualized treatment plan, to control the complications resulting from hyper- or hypoglycemia. For this purpose, we use HbA1c, continuous glucose monitoring (CGM) with TIR (time in range), or blood glucose monitoring (BGM). However, none of the above, can be applied without the cooperation of the patient, which for various reasons, often bec...

Introduction: Patients with Graves’ disease (GD) and thyroid nodules have an elevated risk of developing papillary thyroid carcinoma (PTC). Distant metastasis observed in 1-9% of patients with PTC. The classical subtype usually demonstrates favorable prognosis compared to other more aggressive PTC subtypes, for which an increased risk of extranodal metastases is observed.Aim of the Study: We present an unusual case of a young male diagnosed with cla...

Introduction: Thyroid autoimmunity and diabetes mellitus type 2 (DM2) are the commonest endocrine disorders in the general population. The aim of the study was to investigate whether there is an association between thyroid autoimmunity and β-cell secretion in patients with impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT).Methods/design: 501 patients (381 females) 46.5±14.2 years with IFG and/or IGT and autoimmune thyroidit...

Introduction: HIV infection has been associated with bone loss and increased frequency of bone fractures. The main pathogenetic mechanisms involve the direct effect of the virus and the HIV-induced inflammatory cytokines on bone metabolism, the effect of antiretroviral therapy (cART) per se and the frequently coexisting nutritional disorders and hypogonadism, further accelerating bone loss. Bisphosphonates remain the first-line treatment for these patients. Limited da...

Introduction: Type 2 diabetes mellitus (DM2) is the most common disease in the spectrum of metabolic disorders, with its prevalence increasing significantly in recent years. It is estimated that by 2035, 592 million people will have type 2 diabetes. People with type DM2 have high rates of depression and a quality of life that is poorer than that of the general population. Another important factor in the quality of life of people with DM2 is the compliance of patients with the ...

Introduction: Fine needle aspiration biopsy (FNAB) is the initial investigation of choice for thyroid nodules.Methods: A total of 563 patients (106 males/457 females) underwent FNAB for the same number of thyroid nodules. Their mean age was 56.1±14.1 years. We correlated the demographic profile (age and gender) and sonographic features of these nodules with the FNAB outcome. The Bethesda system for reporting thyroid cytopathology was used.<p cla...

Background: The incidence of endocrine complications among patients with HIV infection has decreased over the last years owing to widespread administration of combined Antiretroviral Therapy (cART) at early stages of the disease. We conducted a prospective observational study aiming to characterize the effects of cART on thyroid function in a cohort of newly diagnosed treatment-naive male patients.Materials and methods: Male subjects diagnosed with HIV i...